Summary
Overview
Work history
Education
Skills
PUBLICATIONS
Symposia
ACADEMIC DUTIES AND RESPONSIBILITIES
Committee
Timeline
Generic

Abdulmohsen M. Al-ruwetie

ARrass

Summary

A highly skilled professional with extensive expertise in tissue culture, including maintenance and analysis of primary cells and cancer cell lines. Proficient in advanced microscopy techniques, flow cytometry, and molecular techniques such as qRT-PCR and gel electrophoresis. Demonstrates strong capabilities in animal handling, particularly with mouse strains for leukaemia research. Experienced in bioinformatics, focusing on gene expression analysis and pathway enrichment. Adept at utilising software tools like Microsoft Office Suite, Graphpad Prism, and Adobe Photoshop for data analysis and presentation. Committed to advancing research in oncology through innovative methodologies and collaborative efforts.

Overview

21
21
years of professional experience

Work history

Associate Professor

College of Applied Medical Science
Buriydah, Qassim
2021.05 - Current
  • Department of Medical Laboratories

Assistant Professor

College of Applied Medical Science
Buriydah, Qassim
2016.03 - 2021.05
  • Department of Medical Laboratories

Assistant Professor

College of Applied Medical Science
Buriydah, Qassim
2016.01
  • Department of medical Laboratory

Lecturer

College of Applied Health science
AL rass
2010.01 - 2016.01
  • Department of medical Laboratories

Demonstrator

College of Applied Health science
AL rass
2007.01 - 2010.01
  • Department of Laboratory

Laboratory Technologist

Royal Commission Hospital
Yanbu
2006.06 - 2007.02
  • Department of Laboratory Medicine

Medical Internship

Al Hada Armed Forces Hospital
Altaif
2005.06 - 2006.06
  • Department of Laboratory Medicine (CAP & AABB)

Education

Doctor of philosophy -

University Of New South Wales (UNSW)

MSC pathological science -

Sheffield Hallam University
Sheffield, UK

Bachelor of Medical Sciences - undefined

Umm Al – Qura University
Makkah (Mecca), Saudi Arabia

Skills

  • Tissue Culture: Maintenance, passaging, freezing and thawing of following primary cells and cancer cell lines (Primary human ALL patient samples, Human ALL Xenografts, Human Mesenchymal stromal cells(hMSC), human leukemia cell lines), preparation of cells for ex vivo cytotoxicity Analysis Drug preparation for in vivo and in vitro analysis, Drug sensitivity testing (MTT and Alamar Blue) and Coculture technique, Ficol Gradient centrifugation
  • Microscopy: Standard and fluorescent Microscope, Trypan Blue exclusion assay
  • Flow Cytometry: Extracellular cell signaling, Human CD markers, Annexin V and PI Staining
  • Molecular Techniques: DNA Isolation/Purification, RNA Isolation/Purification, cDNA library preparation, Amplification, hybridization, Quantitative real-time reverse transcriptase polymerase chain reaction (qRT-PCR), Gel Electrophoresis
  • Animal Handling: Handling of different mouse strains (NSG and NOD/SCID) Intravenous (IV) transplantation of leukaemia cells, monitoring of leukemia engraftment, Harvesting of leukaemia cells from engrafted mice
  • Others: Westren blot, ELIZA
  • Bioinformatics: Gene expression Analysis, Differential gene expression Analysis, pathway enrichment Analysis, protein to Protein interaction Analysis
  • Computer and IT: Microsoft Word, Excel, PowerPoint, Graphpad Prism, Adobe Photoshop, Bioinformatics (SNP and RNA microarray data analysis, Gene pattern, Gene set enrichment analysis, Connectivity Map analysis, Genome studio, FACS diva, (FACS analysis)

PUBLICATIONS

  • Conference Paper: Alruwetie, A. M., Carol, H., Sutton, R., Marshall, G. M., & Lock, R. (2015). Evaluation of Patient-Derived Xenografts for Modeling Outcome of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia. Blood, 126(23), 3759.
  • Ebtehal Alharbi and Alruwetie,A. M (2023). Evaluation Of Genetics Features Of Relapse Disease In Multiple Myeloma Via Bioinformatics. Annals Saudi Hematology Congress (ASHC).
  • Alruwetie, A.M. Utilization of Patient Derived Xenografts (PDX) for Improving Diagnosis, Prognosis and Treatment of Hematological Malignancies (2019). 2019 Saudi LABORATORY AND DIAGNOSTIC CONGRESS. 13-15 October 2019 | Le Méridien Jeddah, KSA.
  • Alruwetie, A.M., Carol, H., Sutton, R., Marshall, G.M., and Lock, R.B. (2015). Utilisation of Patient-Derived Xenograft Models to Improve Relapse Prediction in Intermediate Risk Paediatric Acute Lymphoblastic Leukaemia (poster presentation). ASMR Scientific Meeting 2015, Sydney, NSW, Australia.
  • Alruwetie, A.M., Carol, H., Sutton, R., Marshall, G.M., and Lock, R.B.(2014): Utilisation of Patient-Derived Xenograft Models to Improve Relapse Prediction in Intermediate Risk Paediatric Acute Lymphoblastic Leukaemia (Poster presentation). New Directions in Leukaemia Research Meeting 2014, Noosa, QLD, Australia.
  • Shahin, H. A., Alrashdi, S. A., Alkashgari, H. R., Shalabi, A., Elnour, A. A., Alruwetie, A. M.,…Anwar, F. (2026). Iron status and fetal hemoglobin in transfusion-dependent sickle cell anemia: A cross-sectional comparative study from Al-qunfudah, Saudi Arabia. Journal of Medicinal and Pharmaceutical Chemistry Research, 8(8), 1954-1962.
  • Alruwetie, A. M. (2026). Multi-Compartment Transcriptomics Identifies a Persistent Inflammatory Program and a Network-Derived Diagnostic Signature in Polycythemia Vera. Int J Mol Sci, 27(10).
  • Alzahrani, H. A., Almaghrabi, R. O. M., Alharbi, R., Alghamdi, A. S., Albanghali, M. A., Alyahyawi, H. E.,…Hjar, S. H. (2026). Multidimensional Predictors of Disease Severity and Health Outcomes in Patients with Sickle Cell Disease: A Data-Driven Clinical Insight. Saudi Medical Journal, 47(8), 1322-1333.
  • Akhtar, M. S., Alharbi, R. A., Talat, A., Sindi, A. A., Shanawaz, M. A., Zaeri, A. A.,…Marghani, D. K. (2025). Allele frequency of CTLA-4 rs231775 (+49 A>G) gene polymorphism and its association with cancer susceptibility in the Saudi Arabian population and other ethnic groups. Cell Mol Biol , 71(11), 31-37
  • Hameed, A. R., Fakhri Ali, S., N Almanaa, T., Aljasir, M. A., Alruwetie, A. M., Sanami, S.,…Ahmad, S. (2025). Exploring the hub genes and potential drugs involved in Fanconi anemia using microarray datasets and bioinformatics analysis. J Biomol Struct Dyn, 43(7), 3297-3310.
  • Awwaadh B., Mohammed, A. H., Alharbi, B. F., Alruwetie, A., Sarwar, T., Alharbi, H. O., & Alhumaydhi, F. (2024). Association of thyroid hormones with the severity of chronic kidney disease: a cross-sectional observational study at Tabuk, Saudi Arabia. PeerJ, 12, e18338.
  • Mohammed, A. H., Aljarallah, A. S., Huq, M., Mackawy, A. M. H., Alharbi, B. F., Almutairi, K. S.,…Wasti, A. Z. (2024). Evaluation of the immune system status and hematological dyscrasias, among amphetamine and cannabis abusers at Eradah Hospital in Qassim, Saudi Arabia. Sci Rep, 14(1), 10600.
  • Akhtar, M. S., Akhter, N., Talat, A., Alharbi, R. A., Sindi, A. A. A., Klufah, F.,…Khan, M. J. (2023). Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression. Oncotarget, 14, 528-541.
  • Khan, M. A., Khan, A., Alzohairy, M. A., Alruwetie, A. M., Alsalhi, M. A., Allemailem, K. S.,…Malik, A. (2022). Encapsulation of MERS antigen into α-GalCer-bearing-liposomes elicits stronger effector and memory immune responses in immunocompetent and leukopenic mice. J King Saud Univ Sci, 34(5), 102124.
  • Ziab, Z. A.-a., Ahmed, M. A., Sultan, S. A.-a., Abdulmohsen, A. M., & Raed, A. A. (2022). Clinical Characteristics among Patients with COVID-19: A Single-Center Experience from Medina, Saudi Arabia. Journal of Pure and Applied Microbiology, 16, 1673-1681.
  • Khan, M. A., Malik, A., Alruwetie, A. M., Alzohairy, M. A., Alhatlani, B. Y., Al Rugaie, O.,…Khan, A. (2022). Delivery of MERS antigen encapsulated in α-GalCer-bearing liposomes elicits stronger antigen-specific immune responses. J Drug Target, 30(8), 884-893.
  • Khan, M. A., Malik, A., Alzohairy, M. A., Alruwetie, A. M., Alhatlani, B. Y., Al Rugaie, O. A., & Khan, A. (2022). Liposome-Mediated Delivery of MERS Antigen Induces Potent Humoral and Cell-Mediated Immune Response in Mice. Molecules, 27(2).
  • Alruwetie, A. M. (2021). Evaluation Of SARS-CoV-2 Entry Factors In Chronic Lymphocytic Leukemia Via Bioinformatics Analysis. European Journal of Molecular & Clinical Medicine, 7(10), 2223-2233.
  • Akhter, N., Dar, S. A., Haque, S., Wahid, M., Jawed, A., Akhtar, M. S.,…Ahmad, A. (2021). Crosstalk of Cyclin-dependent kinase inhibitor 1A (CDKN1A) gene polymorphism with p53 and CCND1 polymorphism in breast cancer. Eur Rev Med Pharmacol Sci, 25(12), 4258-4273.
  • Alhumaydhi, F. A., Mackawy, A. M. H., Morgan, E. N., Al Abdulmonem, W., Alsagaby, S. A., Alwashmi, A. S. S.,…Mousa, A. M. (2021). Potential role of folic acid in preventing male infertility associated with MTHFR gene C677T (rs1801133) polymorphism. All Life, 14(1), 730-743.
  • Shahnawaz Khan, M., Mabood Husain, F., Alhumaydhi, F. A., Alwashmi, A. S. S., Tabish Rehman, M., Alruwetie, A. M.,…Shamsi, A. (2021). Exploring the molecular interactions of Galantamine with human Transferrin: In-silico and in vitro insight. Journal of Molecular Liquids, 335, 116227.
  • Khan, A., Aljarbou, A. N., Aldebasi, Y. H., Allemailem, K. S., Alsalhi, M. A., Khan, S.,…Khan, M. A. (2020). Fatty Acid Synthase (FASN) siRNA-Encapsulated-Her-2 Targeted Fab’-Immunoliposomes for Gene Silencing in Breast Cancer Cells. International Journal of Nanomedicine, 15, 5575.
  • Khan, S. H., Younus, H., Allemailem, K. S., Almatroudi, A., Alrumaihi, F., Alruwetie, A. M.,…Khan, M. A. (2020). Potential of Methylglyoxal-Conjugated Chitosan Nanoparticles in Treatment of Fluconazole-Resistant. Int J Nanomedicine, 15, 3681-3693.
  • Akhtar, M. S., Akhter, N., Najm, M. Z., Deo, S. V. S., Shukla, N. K., Almalki, S. S. R.,…Husain, S. A. (2020). Association of mutation and low expression of the CTCF gene with breast cancer progression. Saudi Pharmaceutical Journal, 28(5), 607-614.
  • Toraih, E. A., Fawzy, M. S., Abushouk, A. I., Shaheen, S., Hobani, Y. H., Alruwetie, A. M.,…Badran, D. I. (2020). Prognostic value of the miRNA-27a and PPAR/RXRα signaling axis in patients with thyroid carcinoma. Epigenomics, 12(20), 1825-1843.
  • Alruwetie, A. M., Bendak, K., Yadav, B. D., Carol, H., Evans, K., Mayoh, C.,…Lock, R. B. (2020). Examining treatment responses of diagnostic marrow in murine xenografts to predict relapse in children with acute lymphoblastic leukaemia. Br J Cancer, 123(5), 742-751.
  • Alharbi, R. A., Alwajeeh, T. S., Assabri, A. M., Almalki, S. S. R., Alruwetie, A., & Azazy, A. A. (2019). Intestinal parasitoses and schistosome infections among students with special reference to praziquantel efficacy in patients with schistosomosis in Hajjah governorate, Yemen. Ann Parasitol, 65(3), 217-223.
  • Alruwetie, A. M., Carol, H., Sutton, R., Marshall, G. M., & Lock, R. B. (2015). Evaluation of Patient-Derived Xenografts for Modeling Outcome of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia. Blood, 126(23), 3759-3759.
  • Precision Oncology Saudi Summit (POSS 2026): New frontiers in cancer biology and treatment. 12-14 feb 2026, King Salman International Convention Center, Madinah, Saudi Arabia.
  • 2019 Saudi LABORATORY AND DIAGNOSTIC CONGRESS: 13-15 October 2019 | Le Méridien Jeddah.
  • Recent treatment of Hematological Malignancies, Saudi Society of blood Disorders. 9/06/2020, (Online attendance). Saudi Arabia, 15-16/2/2019
  • 4MAT leadership Training Program, Cairo, Egypt 27-31/10/2019
  • Nature Masterclass Workshop. Deanship of Scientific Research, Qassim University. 7-8/10/2019 .
  • Hematology Year Review 2019, Saudi Society of blood and Marrow transplantation, Riyadh, 15-16/2/2019.
  • Writing Self Study report” College of Applied Health Science, 28-29/8/1438 H
  • - 1st scientific day of Cancer Research, College of Science, Majmaah University, 13-7-2017.
  • New Faculty mentoring program, University Development Deanship, 12-16, 2, 2017

Symposia

  • Precision Oncology Saudi Summit (POSS 2026): New frontiers in cancer biology and treatment. 12-14 feb 2026, King Salman International Convention Center, Madinah, Saudi Arabia.
  • 2019 Saudi LABORATORY AND DIAGNOSTIC CONGRESS: 13-15 October 2019 | Le Méridien Jeddah.
  • Recent treatment of Hematological Malignancies, Saudi Society of blood Disorders. 9/06/2020, (Online attendance). Saudi Arabia, 15-16/2/2019
  • 4MAT leadership Training Program, Cairo, Egypt 27-31/10/2019
  • Nature Masterclass Workshop. Deanship of Scientific Research, Qassim University. 7-8/10/2019 .
  • Hematology Year Review 2019, Saudi Society of blood and Marrow transplantation, Riyadh, 15-16/2/2019.
  • Writing Self Study report” College of Applied Health Science, 28-29/8/1438 H
  • - 1st scientific day of Cancer Research, College of Science, Majmaah University, 13-7-2017.
  • New Faculty mentoring program, University Development Deanship, 12-16, 2, 2017

ACADEMIC DUTIES AND RESPONSIBILITIES

Qassim University, Participate in four community services campaigns by Qassim University campaign

Committee

  • Medical Laboratories Department Council board , 2017- current.
  • Member of the Postgraduate Study Committee at the College of Applied Medical Science
  • Member of the QU Health Ethics Committee. 2019-current.
  • Member of the Committee appointed for interviewing newly accepted Medical Laboratories students, BSc Programs 2,17-current.
  • Member of the QU Health research Ethics committee 2018.

Timeline

Associate Professor

College of Applied Medical Science
2021.05 - Current

Assistant Professor

College of Applied Medical Science
2016.03 - 2021.05

Assistant Professor

College of Applied Medical Science
2016.01

Lecturer

College of Applied Health science
2010.01 - 2016.01

Demonstrator

College of Applied Health science
2007.01 - 2010.01

Laboratory Technologist

Royal Commission Hospital
2006.06 - 2007.02

Medical Internship

Al Hada Armed Forces Hospital
2005.06 - 2006.06

Bachelor of Medical Sciences - undefined

Umm Al – Qura University

Doctor of philosophy -

University Of New South Wales (UNSW)

MSC pathological science -

Sheffield Hallam University
Abdulmohsen M. Al-ruwetie